IGFBP3 Methylation Is a Novel Diagnostic and Predictive Biomarker in Colorectal Cancer

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IGFBP3 Methylation Is a Novel Diagnostic and Predictive Biomarker in Colorectal Cancer

BACKGROUND AND AIM Aberrant hypermethylation of cancer-related genes has emerged as a promising strategy for the development of diagnostic, prognostic and predictive biomarkers in human cancer, including colorectal cancer (CRC). The aim of this study was to perform a systematic and comprehensive analysis of a panel of CRC-specific genes as potential diagnostic, prognostic and predictive biomark...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0104285